Biomedical Image Analysis

Magnetic Resonance Imaging (MRI) is an important diagnostic tool in modern medicine. The data acquisition, the storage and the statistical analysis of the data, the segmentation of images, the elimination of artefacts and noises are just some examples of issues for which mathematical and informatic tools should be considered and implemented.

After the image denoising, fiber tracking is performed to study the diffusion of water on a microscopic scale, analyzing the diffusion tensor and studying the relevant properties along the brain fibers (like Fractional Anisotropy, Mean, Radial and Axial Diffusivity). Statistical anaylis is required to take into account correlations and spatial distributions, linking them with the other eventually relevant parameters like age and sex of people belonging to patients or controls subgroups.

Since many parameters are involved, a database approach is required, as well as a user interface to different tools, from visualization to statistical analysis and reporting; for this, galaxy has been taken into account (images from Wikipedia)